KIRKSVILLE - The Lady Hornets tumbled to 6-13 on the season and 2-5 in the North Central Missouri Conference after falling to the Lady Tigers on Saturday afternoon.
Fulton trailed 9-1 after one quarter and 24-9 at the break. The Lady Hornets were down 40-17 entering the fourth quarter.
Senior guard Kayanna Gaines led Fulton with 10 points.
"The game just did not go our way," Lady Hornets head coach Matt Wilbers said. "We had a long road trip (here) and a long road trip last night (to Hannibal) and lost a tough one, and used up a lot of energy and emotion.
"I was proud of the fact that the girls didn't give up and decided to battle in the fourth quarter."
Corinne Vorkink directed Kirksville (10-9, 6-2) with a game-high 16 points. The Lady Tigers swept the season series with the Lady Hornets after prevailing 45-33 on Feb. 12 in Fulton.
On Friday night in Hannibal, the Lady Hornets were outscored by the Lady Pirates 10-4 in overtime in suffering a 44-38 NCMC loss.
The contest was close throughout, with Fulton trailing 10-9 after one quarter. The two teams were tied at 15-all at halftime and 23-all after three quarters.
The Lady Hornets forced overtime when senior forward Sydney Hedgpath banked in a 3-pointer from the right wing with 1 second left in regulation, tying the game again at 34-all.
"The girls made something out of nothing (on the play) and Sydney had the confidence to take a big shot," Wilbers said.
Hedgpath was the only player to reach double figures for the Lady Hornets, producing 20 of her game-high 25 points in the second half and overtime. She finished with four 3s.
"I thought the girls played really hard, but we've only been in the gym three times in the last two weeks (because of the weather)," Wilbers said. "It's hard to come up with a consistent game plan.
"The girls kept getting frustrated with the fact that we couldn't hit any shots. We knew coming in they'd be a little rusty."
Sydney Hart supplied 16 points to pace Hannibal, which earned its first NCMC win of the season by avenging a 51-17 loss to the Lady Hornets on Dec. 8 in Fulton.
Allison Hull added 10 points for the Lady Pirates on Friday night.
"They got a second chance at us," Wilbers said. "We knew they'd give us a good game."
The Lady Hornets host NCMC rival Mexico at 6 p.m. Monday at Roger D. Davis Gymnasium. Fulton lost to the Lady Bulldogs 44-38 on Feb. 2 in Mexico.