NEW BLOOMFIELD - Senior center Easton Ambler scored 13 points as the Wildcats dropped to 2-10 on the season after being overpowered by the Panthers on Friday night.
New Bloomfield fell behind 21-8 after one quarter and was down 45-13 at the break.
Junior guard Breycin Dysart chipped in with 11 points for the Wildcats.
Guy Moran topped Centralia with a game-high 24 points.
New Bloomfield is the No. 8 seed for this week's South Callaway Invitational Tournament. The Wildcats clash with top-seeded Hermann in the first round at 6 p.m. Tuesday in the middle school gym.