The Lady Hornets suffered their second loss in a row, dropping their home and North Central Missouri Conference opener to the Lady Owls on Thursday night at Roger D. Davis Gymnasium.
Fulton (2-3) fell behind 17-7 after one quarter and trailed 28-17 at halftime. Marshall outscored the Lady Hornets 22-13 in the third quarter to expand its lead to 50-30.
Sophomore forward Carly Fisher tallied 14 points and seven rebounds to pace Fulton. Senior center Haden Trowbridge chipped in with nine points and 13 rebounds, while sophomore forward Sydney Hedgpath finished with nine points and four rebounds.
"There were times that we had good stretches," Lady Hornets head coach TJ Quick said. "We worked the ball like we were supposed to and got a great shot or a foul.
"There were times that we struggled. We just have to try to piece together a good quarter, then a good half and then all four quarters."
Kassidy Heying led Marshall with a game-high 20 points.
Fulton travels to Boonville at 6:30 p.m. Tuesday.