The Lady Owls fell to 1-4 on the season after being shut out by the Lady Wildcats on Tuesday night at Firley Field.
Both teams finished with 16 shots, but William Woods University was outshot 10-5 in shots on goal. The Lady Owls - who have lost two straight - had a 6-4 edge in corner kicks.
William Woods travels to Fayette to face Central Methodist University at 5 p.m. Saturday.