The Owls were outscored by the Hornets 12-4 in the final minutes in dropping their second in a row in Saturday's American Midwest Conference loss at Anderson Arena.
William Woods University — which trailed 32-24 at halftime — took a 55-54 lead when junior guard Treshawn Gause made two free throws with 2 minutes, 12 seconds to play. Harris-Stowe State University, though, went back in front to stay on its ensuing possession after Nate Rigmaiden converted a pair of free throws with 1:55 remaining.
The Hornets were 6-of-6 from the foul line in the last :35 to seal the win. Harris-Stowe — redeeming itself after a 78-71 home loss to the Owls on Jan. 22 — improved to 15-9 on the season and 10-8 in the AMC.
William Woods is also 15-9 overall and fell to 12-5 in conference play.
Junior forward David Johnson Jr. produced 17 points to guide the Owls, who shot just 39 percent (21-of-54) as a team. Gause added 12 points.
Johnson Jr. and sophomore forward Makenzie Fessler both collected six rebounds as William Woods was outrebounded 40-33.
Deandre Clark connected for a game-high 24 points to lead three players in double figures for the Hornets, who shot 40 percent (23-of-57) from the field. Riley Barnes contributed 11 points and Calvin Giles Jr. finished with 10.
The Owls travel to Lindenwood University-Belleville (Illinois) for an AMC game at 7:30 p.m. Tuesday. William Woods toppled Lindenwood-Belleville 78-64 on Jan. 8 in Fulton.